Somatic Stem cell Aging

Adult stem cells exist in most mammalian organs and tissues and are fundamental for ordinary tissue homeostasis and repair. In many tissues, there is an age-related decrease in undeveloped cell usefulness however not an exhaustion of undifferentiated cells. Such practical changes reflect malicious impacts of age on the genome, epigenome, and proteome, some of which emerge cell independently and others of which are forced by an age-related change in the nearby milieu or systemic environment. Outstandingly, a portion of the progressions, especially epigenomic and proteomic, are possibly reversible, and both natural and hereditary mediations can bring about the revival of matured undeveloped cells. Such discoveries have significant ramifications for the stem cell– based treatment of age-related illnesses.

  • Mesenchymal stem cell aging
  • Hematopoietic stem cell aging
  • Embryonic stem cell aging
  • Pluripotent stem cell aging
  • Epithelial stem cell aging
  • Oncogene induced senescence
  • Tissue regeneration
  • Genomic instability
  • Genomic instability
  • Aging and holistic medicine

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